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Cilostazol - Interactions and Warnings

The most common adverse effects involve the gastrointestinal tract and central nervous system. Inhibitors of cytochrome P-450 isoenzymes 3A4 and 2C19 should be used cautiously in patients taking cilostazol, and this drug is contraindicated in patients with congestive heart failure.
- Am J Health Syst Pharm 2001 Mar 15;58(6):485-93; quiz 494-6 -- Treatment of intermittent claudication with pentoxifylline and cilostazol. -- Tjon JA, Riemann LE.

Potentially dangerous interactions can occur with a variety of prescription and non prescription drugs. Consult with your physician before taking any drugs, herbs or supplements.

Absorption of cilostazol decreased approximately 15% when it was given with lovastatin. Grapefruit juice should be avoided.
- Clin Pharmacokinet 1999;37 Suppl 2:69-77 -- Effect of multiple cilostazol doses on single dose lovastatin pharmacokinetics in healthy volunteers. -- Bramer SL, Brisson J, Corey AE, Mallikaarjun S.

Not recommended if you are pregnant or breastfeeding. Avoid alcohol. Older people may experience more side effects.

last update: November 2008

This information is not intended to be a substitute for professional medical advice. You should not use this material to diagnose or treat a health condition or disease without consulting with your healthcare provider.
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