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Reishi Side Effects, Interactions and Warnings

  • The extract decreased systolic and diastolic blood pressure, which was accompanied by an inhibition of renal efferent sympathetic nerve activity. Concluded that the mechanism of hypotensive action of Ganoderma lucidum was due to its central inhibition of sympathetic nerve activity.
    - Chem Pharm Bull (Tokyo) 1990 May;38(5):1359-64 -- Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. -- Lee SY, Rhee HM.

  • May cause allergic reaction. The compiled data suggests that there are common as well as specific allergenic components in two extracts studied.
    - J Investig Allergol Clin Immunol 2000 Mar-Apr;10(2):83-9 -- Ganoderma lucidum: partial characterization of spore and whole body antigenic extracts. -- Gupta SK, Pereira BM, Singh AB.

  • Reishi is a mushroom - may be wise to avoid if you are allergic to mushrooms.

  • Respiratory allergy sufferers should use caution. Avoidance is recommended for better management of respiratory allergy.
    - Indian J Pediatr 2002 Mar;69(3):245-50 -- Common environmental allergens causing respiratory allergy in India. -- Singh AB, Kumar P.

  • The aim of this study was to assess the efficacy and safety of two different types of medical mushrooms in patients with prostate cancer. According to the results they found that no significant anticancer effects were observed with the intake of these two medical mushrooms.
    - Medical mushrooms used for biochemical failure after radical treatment for prostate cancer: an open-label study. -- Yoshimura K, Kamoto T, Ogawa O, Matsui S, Tsuchiya N, Tada H, Murata K, Yoshimura K, Habuchi T, Fukushima M. -- Int J Urol. 2010 Jun;17(6):548-54. Epub 2010 Apr 19.

last update: March 2014

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