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Boron Side Effects, Interactions and Warnings

  • Dietary supplements of boron may enhance the effects of estrogen.
    - Biol Trace Elem Res 2001 Summer;82(1-3):109-23 -- Dietary boron supplementation enhanced the action of estrogen, but not that of parathyroid hormone, to improve trabecular bone quality in ovariectomized rats. -- Sheng MH, Taper LJ, Veit H, Qian H, Ritchey SJ, Lau KH.

  • A diuretic effect of Boron was noted during high dose administration.
    - Int Arch Occup Environ Health 2000 Jun;73 Suppl:S98-100 -- Pharmacokinetics and effects after intravenous administration of high-dose boron to rat. -- Tagawa T, Kono K, Dote T, Usuda K, Nishiura H, Koizumi C, Saito M, Nakaya H, Nagaie H.

  • Supplementation with 10 mg of Boron resulted in the recovery of 84% of the dose in the urine and a significant increase in plasma estradiol concentration, but no effect on plasma lipoproteins. In rats, increasing the intake of B through the drinking water is reflected in the tissue concentrations, results in an increase in plasma testosterone and vitamin D, and results in a decrease in HDL cholesterol. It is clear that Boron has the potential to impact significantly on a number of metabolic processes.
    - Biol Trace Elem Res 1998 Winter;66(1-3):227-35 -- The nutritional and metabolic effects of boron in humans and animals. -- Samman S, Naghii MR, Lyons Wall PM, Verus AP.

  • Boron stimulates yeast (Saccharomyces cerevisiae) growth
    - J Nutr 1999 Dec;129(12):2236-8 -- Boron stimulates yeast (Saccharomyces cerevisiae) growth. -- Bennett A, Rowe RI, Soch N, Eckhert CD.

  • Boron supplementation markedly elevated the serum concentrations of 17 beta-estradiol and testosterone; the elevation seemed more marked when dietary magnesium was low.
    - FASEB J 1987 Nov;1(5):394-7 -- Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women. -- Nielsen FH, Hunt CD, Mullen LM, Hunt JR.

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  • last update: February 2014

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