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Inositol Side Effects, Interactions and Warnings

  • Use caution if you have depression or bipolar disorder and are taking or considering taking inositol. There is a possibility that manic episodes may occur.
    - Levine J, Witztum E, Greenberg BD, et al. -- Inositol-induced mania?. -- Am J Psychiatry. 1996;153:839.

  • Inositol interacted with lithium when rearing behavior was measured. More specific interactions were found between lithium and inositol following cholinergic and serotonergic stimulation. Inositol attenuated lithium-pilocarpine seizures and the enhancement of the serotonin syndrome.
    - Eur Neuropsychopharmacol 1999 Sep;9(5):385-97 -- Interactions of lithium and drugs that affect signal transduction on behaviour in rats. -- Kofman O, Patishi Y.

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  • last update: February 2014

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