Vitamin B1

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Vitamin B1 Side Effects, Interactions and Warnings



  • Anaphylaxis as an adverse systemic reaction to thiamine (Vitamin B1) has been described in the literature since 1938. Although its precise mechanism is still uncertain, the reaction appears to involve immediate type hypersensitivity and to be exclusively related to parenteral administration. The following case report is a reminder of this reaction to thiamine which may be administered by general practitioners, emergency physicians and internists.
    - Schweiz Med Wochenschr 1998 Oct 31;128(44):1743-4 -- Anaphylaxis to parenteral thiamine (vitamin B1). -- Morinville V, Jeannet-Peter N, Hauser C.

  • The isolated administration of vitamin B1, without concomitant vitamin B6 and nicotinamide may precipitate potentially life-threatening pellagra encephalopathy.
    - Schweiz Med Wochenschr 1996 Apr 13;126(15):607-11 Vitamins and metals: possible hazards for humans -- Ballmer PE.




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  • last update: February 2014



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