Dong quai may increase the effects of antidepressants due to the fact that it may alter serotonin levels in the brain.
-Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis. — Deng S, Chen SN, Yao P, Nikolic D, van Breemen RB, Bolton JL, Fong HH, Farnsworth NR, Pauli GF. — J Nat Prod. 2006 Apr;69(4):536-41.
Since the effects of Dong Quai have not been fully evaluated during pregnany or breastfeeding, it is not recommended. If you experience excessive menstrual flow, stop using the product.
– Murray, M. — The Pill Book Guide to Natural Medicines: Vitamins, Minerals, Nutritional Supplements, Herbs, and Other Natural Products. — Bantam, 2002. 624-625.
Dong quai has been associated with documented reports of potential interactions with warfarin. It is not recommended for people taking blood-thinning agents.
– Am J Health Syst Pharm 2000 Jul 1;57(13):1221-7; quiz 1228-30 — Potential interactions between alternative therapies and warfarin. — Heck AM, DeWitt BA, Lukes AL.