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Brand Name: Synercid®
Active Ingredient:   quinupristin/dalfopristin
Strength(s): 500 mg (150mg of quinupristin and 350mg of dalfopristin)
Dosage Form(s):   Powder for injection
Company Name:    Rhone-Poulenc Rorer
Prescription only
*Date Approved by the FDA:   September 21, 2022
*Approval by FDA does not mean that the drug is
available for consumers at this time.

What is Synercid used for?

Synercid is used to treat adult
patients with serious or life-threatening infections and certain skin infections caused by
specific types of bacteria.

Synercid was approved based on its ability to clear bacteria from the
bloodstream. At this time, it is not known if Synercid will cure the underlying infection.
Clinical studies to determine Synercid’s ability to cure underlying infection are
presently under way.

Special Warnings with Synercid:

  • Synercid can interact with many medications. Review ALL medications that you are
    taking with your health care provider, including those that you take without a
  • Tell your health care provider if you are taking cyclosporine, midazolam, or

General Precautions with Synercid:

  • Tell your health care provider right away if you develop diarrhea while taking
  • Tell your health care provider if you are trying to become pregnant, are already
    pregnant, or are breast-feeding.
  • Irritation of the vein can occur when Synercid is given. Therefore, it is
    recommended to flush the vein with 5% Dextrose in Water following completion of the
  • Do not dilute Synercid with Saline solution.

How is Synercid given?

Synercid is given by IV in a hospital setting.

What are some possible side effects of Synercid? (This is NOT
a complete list of side effects reported with Synercid. Your health care provider can
discuss with you a more complete list of side effects.

  • Pain, swelling, and irritation at the infusion site
  • Muscle and joint pain
  • Nausea
  • Vomiting
  • Rash
  • Diarrhea
  • Headache
  • Itching

For more detailed information about Synercid, ask your health care provider.    Synercid’s labeling



Back to Drug Side Effects

source: FDA

last update: December 2004

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